Advil Extra Strength Liqui-Gels work Liquid-Fast to relieve headaches, muscle and back pain, as well as migraine pain and migraine symptoms of nausea and sensitivity to light and sound. They also provide fast, effective pain relief from toothaches, tension headaches, muscle sprains and strains, dental pain, and pain from inflammation associated with arthritis or physical overexertion. Engineered to relieve pain at the site of inflammation, Advil Liqui-Gels start working within 30 minutes — taking pain out of the picture so you can get on with your day or get to sleep at night. Containing a liquid form of ibuprofen that quickly absorbs into your body and rushes relief right to where it hurts, a dose of Advil Extra Strength Liqui-Gels provides up to 8 hours of pain relief. Advil has provided fast, effective fever and pain relief for over 25 years. This package includes one 12-count bottle of Advil Extra Strength Liqui-Gels (400 mg ibuprofen). The pain reliever in Advil is ibuprofen, a non-steroidal anti-inflammatory drug (NSAID) that when taken as directed is a fast and effective pain reliever and fever reducer.